The Prosperous left England May 1611 for Virginia, a fleet of three ships and three carvels (?) under Sir Thomas Gates. She was accompanied by the Starr with Captain Christopher Newport, now vice Admiral of Virginia and pilot John Clark, and the Elizabeth, three hundred people, supplies, horses, kine, goats, besides "coneies, pigeons and pullen." They reached the Canaries in April, the Dominica West Indies May 9, Porto Rico and anchored at Point Comfort at night, May 22, 1611. The men were listed as "honest, sufficient artificers, carpenters, smiths, coopers, fishermen, tanners, shoemakers, shipwrights, brickmen, gardeners, husbandmen and laboring men of all sorts." The Prosperous arrived from Virginia November 13, 1611, announcing the arrival of the Spanish ships in Virginia, the "landing of spies."

1611 Voyage:
Askew, William, May 1611 voyage, 30 at muster.
Baley, William, 1611 voyage, 41 at muster. Wife Mary was on the George 1617.
Wilcockes, Mihell, 1611 voyage, aged 31 at muster, Elizabeth City with John Slater anmd 3 servants, wife Elizabeth on Concord.
Willowby, Thomas, 1611 voyage, aged 23 at muster Elizabeth City.

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